These injectables are made from a variety of materials, ranging from polymethylmethacrylate (PMMA) which is what hard contact lenses and Plexi-Glas are made from, to hydrophilic polyacrylamide gel which is regularly used for hydro-seeding and other agricultural applications, protein separation and time released drugs. The race for a safe, yet permanent, solution is on. Most of these substances are designed to be encapsulated by your body's own collagen and remain as a permanent to semi permanent solution for tissue deficiencies simple cosmetic enhancement. Although many of these may seem like a dream come true, many are not yet available in the United States. Well, at least legitimately.
They are also used for augmentation of the lips and for filling out acne scars and other types of tissue deficiencies. They are utilized after a temporary try on product has been used and it is determined that the patient does in fact want permanency. In this section, we will discuss the various options in permanent soft tissue augmentation with the use of injectable micro-implants.
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Amazingel (aka Amazing Gel): (technically: injectable hydrophilic polyacrylamide gel with unknown % residual unpolymerized acrylamide monomer, reportedly under 10 ppm) Manufactured by FuHua high Molecular Matter Company, Ltd. and commercially available since 1998, this product is a medical grade, hydrophilic polyacrylamide gel. It is unknown if this product has antibacterial properties to decrease the chances of bacterial infections. It is said that this product contains both BFGF and EGF. BFGF is an acronym for basic fibroblast growth factor, and EGF stands for epidermal growth factor. The ingredients stimulate elastin production, plus the polyacrylamide gel holds 300 to 400 times its weight in water. The main augmentation feature of the gel is the polyacrylamide gel.
"On Dec.28,2000, Amazingel got registered in China State Drug Administration. It was also listed in the Sparkle Program of the Ministry of Science and Technology of China." -- credit: V & J Tech Co., Ltd. Company Caution: The injection site should be kept free of cosmetics, oils, water, soaps, etc. for a full 24 hours. Failure to do so can result in complications such as infection. Do not touch the treatment area and if you must clean the area, it should be done with a sterile gauze pad and rubbing alcohol. Do not apply any cosmetic creams or moisturizers. Your doctor may have you apply a triple antibiotic ointment with a sterile cotton swab for each injection site.
Aquamid: (technically: injectable hydrophilic polyacrylamide gel (HPG, or PAAG) with 5 ppm residual unpolymerized acrylamide monomer) Manufactured by Danish pharmaceuitcal company, Ferrosan A/S, and distributed by Contura, this product is made of 2.5% hydrophilic polyacrylamide and 97.5% water. Polyacrylamide can hold between 300 and 400 times its weight in water and has been used in medical applications, drug delivery, intraocular lenses, water purification and agriculture for many, many years. It has been used in cosmetic applications for over a decade. The results are immediate and should not be under or over corrected. Aspiration is possible.
As far as I know, this product does not contain any antibacterial elements to decrease the chances of bacterial infection. Polyacrylamide implants are susceptible to bacterial infections several months to years after injection. I have come into contact with several patients who have had infections which occurred several months post-injection.
Caution: The injection site should be kept free of cosmetics, oils, water, soaps, etc. for a full 24 hours. Failure to do so can result in complications such as infection. Do not touch the treatment area and if you must clean the area, it should be done with a sterile gauze pad and rubbing alcohol. Do not apply any cosmetic creams or moisturizers. Your doctor may have you apply a triple antibiotic ointment with a sterile cotton swab for each injection site.
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